Dr Goundry is a leading scientist in the synthesis and manufacture of active pharmaceutical ingredients. Following his D.Phil in organic synthesis at Oxford University and Post Doc at Indiana University Will joined AZ at Macclesfield in 2006. He has developed a strong track record in process design and scale up working from grams to tonnes, including biocatalysis and flow chemistry. Will is currently AstraZeneca’s scientific lead for New Modalities in the early phase. In this role he supports the development and manufacture of antibody drug conjugates (ADC), peptides and oligonucleotide drugs for clinical trials. He is an Honorary Lecturer at the University of Manchester in the Division of Pharmacy, and an industrial lead for both the Centre for Biocatalytic Manufacture of New Modalities and the Centre for Doctoral training (CDT) in integrated catalysis.

Presentation Title: Route Design and Scale-Up of a Topoisomerase I Inhibitor Antibody–Drug Conjugate Payload

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