Speakers

Jules graduated from the University of Newcastle upon Tyne with a 1st Class Honours degree and
subsequently a PhD in Medicinal Chemistry and Anti-cancer Drug Design. This was followed by two
post-doctoral positions, before a move from academia to Onyx. He has over 20 years of industrial
experience in PR and D as Research Manager and is currently Solid State Manager at Onyx and is
responsible for all solid form development and preformulation activities.

Presentation Title: Crystallising a Challenging API – a Pragmatic Approach for Phase 1

Abstract: A significant number of molecules that are selected for development continue to demonstrate challenging physicochemical characteristics. In this presentation we comment on how an integrated and phase appropriate approach to development can overcome these hurdles with specific reference to the final crystallisation of such candidates via a brief case study.

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