Shane completed his chemistry undergraduate study at University College Cork, Ireland in 2011 before earning his PhD at the University of Liverpool. He initially gained experience with transition metal catalysed allylic alkylations before moving to the area of biocatalysis. Following completion of his Ph. D, Shane held a post doctoral position funded by Innovate UK where he applied his biocatalysts methodology to the synthesis of building block chemicals derived from biomass.
Shane started his industrial career at Merck Sharpe & Dohme (MSD), Ballydine, Ireland as a Senior Specialist in Engineering, where he supported the piloting and launch of new global products and provided technical support for the GMP manufacture of APIs on site. Shane is now part of Bristol Myers Squibb’s, Chemical process development (CPD) department and currently leads the BMS UK Moreton Chemistry group. The UK group work as part of a global matrixed team with their sister sites in New Brunswick and Summit, New Jersey to develop safe, innovative and sustainable chemical routes to APIs. In addition, Shane leads the Biocatalysis strategy for CPD.
Presentation Title: Sustainable Manufacturing of BMS-986278 Leveraging an ERED/KRED Biocatalytic Cascade